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Androgenetic Alopecia

Also called: male pattern hair loss · female pattern hair loss · AGA · FPHL

Androgenetic alopecia (AGA) is the most common cause of hair loss worldwide - a genetically determined, hormone-dependent miniaturisation of hair follicles. In men it follows a predictable Norwood–Hamilton pattern; in women it presents as diffuse central thinning (Ludwig scale).

How it happens

DHT (dihydrotestosterone), produced from testosterone by 5α-reductase, binds to androgen receptors in genetically susceptible follicles, shortening the anagen (growth) phase and causing progressive follicle miniaturisation. The dermal papilla gradually shrinks, producing thinner, shorter, and lighter vellus hairs until the follicle becomes completely unproductive.

In India

Affects approximately 50% of men by age 50 and 30–40% of women over their lifetime. Onset in South Asian men often begins in the early-to-mid 20s.

Key symptoms

  • Receding hairline at temples and frontal scalp (men)
  • Widening central part or thinning crown (women)
  • Strands feel finer and break more easily
  • More scalp visible under normal lighting
  • Increased shedding noticed during washing

Common triggers

  • Genetic predisposition (family history is the strongest predictor)
  • Elevated androgen sensitivity
  • Post-partum hormonal shifts (women)
  • PCOS (women)
  • Ageing

How it is diagnosed

  • Trichoscopy - follicle density and hair shaft diameter variability
  • Hair pull test
  • Serum DHEAs, testosterone, and sex hormone binding globulin (women)
  • Thyroid function (to rule out concurrent hypothyroidism)

Tests are performed by a qualified dermatologist or trichologist after clinical assessment.

Treatment options

Topical MinoxidilEvidence A

5% solution or foam applied twice daily prolongs anagen phase. Results visible by month 4–6.

Oral Finasteride / DutasterideEvidence A

5α-reductase inhibitors reduce scalp DHT. Prescription-only; requires dermatologist evaluation.

Trichocycle MatrixEvidence B

A 7-phase vegan cyclical-nutrition therapy (melatonin, vitamin C, curcumin/CoQ10, botanicals) matched to the hair growth cycle. Supports the follicle from within.

View Trichocycle Matrix →
Low-Level Laser Therapy (LLLT)Evidence B

Photobiomodulation stimulates follicle metabolism. Used as adjunct to topical therapy.

Reduce heat styling and tight hairstylesEvidence C

Mechanical traction adds to follicle stress in susceptible scalps.

Timeline: First visible response to topical minoxidil typically at 4–6 months. Plateau usually by month 12. Consistent daily use is required to maintain results.

When to see a doctor

Book a dermatologist consultation if you notice rapid progression (>50% volume loss in 6 months), patchy rather than diffuse loss, scalp inflammation or itching, or if over-the-counter treatments have shown no response after 6 months.

Dermatologist perspective
“In my clinic, the most common mistake I see is stopping topical treatment the moment shedding increases in the first 6 weeks - that "shedding phase" is actually the old miniaturised hairs making way for healthier ones. Persistence is the single biggest predictor of outcome.”
Dr. Abhishek Pilani · Gold Medalist Dermatologist · ISHRS Member · Co-Founder, Assure Clinic

Last reviewed March 2025. This page is clinical reference, not a diagnosis. Only an in-person assessment can tell you which condition you have.

Related conditions

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